A nurse is caring for a client who started taking amitriptyline 6 days ago. The client reports that the medication is not helping. Which of the following responses should the nurse make?

A. Increasing the dose too soon is inappropriate; therapeutic effects take time to manifest. B. Amitriptyline can be taken with or without food; stomach contents do not affect its efficacy. C. Most antidepressants, including amitriptyline, require 2-4 weeks for therapeutic effects. The client needs reassurance and education. D. Switching medications prematurely is unnecessary unless severe side effects occur.