A nurse is caring for a client who was prescribed a nonsteroidal anti-inflammatory drug. For each clinical finding, click to specify whether the finding indicates or does not indicate a therapeutic effect of the drug.

• Improved range of motion: Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce inflammation and pain in affected joints or tissues. Improved range of motion demonstrates decreased swelling, stiffness, and discomfort, indicating that the medication is achieving its therapeutic goal. This outcome reflects functional improvement and enhanced mobility, which are primary objectives of NSAID therapy. • Temperature of 101.3 F (38.5 C): Fever indicates the body is still mounting an inflammatory or infectious response. NSAIDs have antipyretic properties, so persistent elevated temperature suggests that the therapeutic effect is incomplete. Continued fever may require reassessment of the underlying cause or medication effectiveness. • Elevated blood pressure: Increased blood pressure is not a therapeutic effect of NSAIDs. In fact, NSAIDs can sometimes cause fluid retention and raise blood pressure, which is considered an adverse effect rather than a benefit. Monitoring is necessary to prevent cardiovascular complications. • Swelling of the knee: Persistent swelling reflects ongoing inflammation, indicating that the NSAID is not yet fully effective. Reduction in swelling is a desired therapeutic outcome, so continued edema suggests incomplete response or need for additional interventions.