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    Swedish Institute College Of Health Sciences Medical Surgical Proctored Exam

    A nurse is caring for a client with myasthenia gravis who has been prescribed pyridostigmine. Which nursing intervention is most important to include in the care plan for this client?

    Explanation & Rationale

    Rationale: A. Pyridostigmine is an acetylcholinesterase inhibitor that increases acetylcholine at neuromuscular junctions to improve muscle strength. However, overmedication can lead to cholinergic crisis, which presents with muscle weakness, excessive salivation, sweating, bradycardia, and gastrointestinal upset. Monitoring for these signs is critical for patient safety and allows for early intervention, such as holding the medication and administering anticholinergic agents (e.g., atropine) if necessary. B. Pyridostigmine must be taken consistently as prescribed. Stopping the medication abruptly can lead to rebound weakness or myasthenic crisis, which can be life-threatening. C. While taking pyridostigmine 30–60 minutes before meals can improve absorption and help with swallowing, this is important but not the highest priority intervention. Monitoring for adverse effects takes precedence for patient safety. D. Pyridostigmine is usually administered orally or intravenously, and self-injection is not standard practice. Teaching injection techniques is unnecessary unless the healthcare provider prescribes an alternative route, which is rare.

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