A nurse is caring for a group of clients diagnosed with polycystic kidney disease (PKD). While teaching about ways to slow the progression to end-stage renal disease (ESRD), which of the following topics would be most important for the nurse to include?

A. Blood glucose control is essential in diabetic nephropathy, but not the primary concern in PKD unless the client also has diabetes. B. Fluid restriction may be required in advanced stages, but it does not slow disease progression. C. Blood pressure control is the most important intervention in slowing the progression of PKD to ESRD. Uncontrolled hypertension accelerates cyst growth and kidney damage. D. While pain management is important for quality of life in PKD, it does not impact disease progression.