A nurse is caring for a patient with thrombotic thrombocytopenic purpura who is having plasmapheresis every day. Which assessment alerts the nurse of a complication?

A. Seizure activity: While TTP itself can cause neuro symptoms, seizures during the procedure often point to electrolyte imbalances. B. Hypotension: Plasmapheresis involves removing and replacing plasma. Rapid fluid shifts during the procedure can lead to hypovolemia and hypotension. C. Diarrhea: This is not a common or recognized complication of the plasmapheresis procedure. D. Intense headache: While possible due to blood pressure changes, hypotension is a more immediate and life-threatening hemodynamic complication during the procedure.