A nurse is caring for an 86-year-old client with moderate Alzheimer's disease who has become increasingly agitated and verbally aggressive in the evenings. The provider considers initiating an antipsychotic medication.

A. Antipsychotics for long-term prevention: Long-term routine antipsychotic use for behavioural symptoms (without psychosis) is discouraged because of safety concerns and limited benefit. B. Atypical antipsychotics are FDA-approved and pose no greater risk than placebo: There is an FDA boxed warning and evidence showing increased mortality and serious adverse events in older adults with dementia receiving antipsychotics. C. Antipsychotics carry an increased risk of mortality in older adults with dementia and should only be used after nonpharmacologic strategies fail: Best practice is to try nonpharmacologic, individualized behavioral strategies first; antipsychotics may be considered only when symptoms are severe, dangerous, or refractory - using lowest effective dose and regular reassessment. D. Antipsychotics are a first-line treatment and generally well tolerated: This is not supported for dementia-related behavioral symptoms because of risk/benefit concerns in this population.