A nurse is collecting data from a client who reports cessation of nicotine use. Which of the following manifestations should the nurse expect? (Select all the apply.)

A. Decreased appetite: Nicotine withdrawal typically causes an increase in appetite rather than a decrease. Clients may experience cravings for food as a substitute for nicotine, making decreased appetite an unlikely manifestation during cessation. B. Restlessness: Restlessness and irritability are common symptoms of nicotine withdrawal. The nervous system responds to the absence of nicotine stimulation, leading to agitation, anxiety, and difficulty remaining calm. C. Weight gain: Weight gain frequently occurs after nicotine cessation because metabolism may slow and caloric intake often increases as clients substitute food for nicotine. This is a well-documented effect during withdrawal. D. Difficulty concentrating: Nicotine stimulates the central nervous system, so withdrawal can impair attention and focus. Clients may report trouble concentrating, memory lapses, or mental fog during the early stages of cessation. E. Diarrhea: Diarrhea is not typically associated with nicotine withdrawal. Gastrointestinal effects during withdrawal usually involve constipation rather than diarrhea due to decreased gastrointestinal motility.