A nurse is completing an admission assessment for a client who has been taking St. John’s wort.The nurse should identify that which of the following medications can interact with St. John’s wort?
Explanation & Rationale
Choice A rationaleRifampin is an antibiotic used to treat infections, and it does not interact with St. John’s wort. Its pharmacokinetic properties do not overlap with St. John’s wort.Choice B rationaleFurosemide is a diuretic used to treat fluid retention and hypertension. It does not have known interactions with St. John’s wort, as they affect different pathways in the body.Choice C rationaleSt. John’s wort can interact with citalopram by increasing the risk of serotonin syndrome, a potentially life-threatening condition characterized by excessive serotonergic activity in the central nervous system.Choice D rationaleAllopurinol is used to manage gout by reducing uric acid levels. It does not interact with St. John’s wort, as they affect different metabolic processes in the body.