A nurse is creating a plan of care for a pediatric client who has been diagnosed with osteosarcoma and will be receiving chemotherapy with radiation interventions. The nurse should monitor the client for which of the following expected adverse effects? (Select All that Apply.)

A. Nausea is a common side effect of both chemotherapy and radiation therapy. Antiemetics are often used to manage this adverse effect. B. Hair loss is a well-known side effect of chemotherapy, as it affects rapidly dividing cells, including those in hair follicles. Radiation therapy to the head or neck area can also cause localized hair loss. C. Diarrhea is a potential side effect of chemotherapy and radiation, particularly when the digestive tract is affected. Some chemotherapies and radiation treatments irritate the gastrointestinal system, leading to diarrhea. D. Skin Sensitivity can result from radiation therapy, especially in the treated area. The skin may become red, irritated, and sensitive. E. Weight gain is not typically associated with chemotherapy or radiation therapy. In fact, many children experience weight loss due to nausea, decreased appetite, or other side effects.