A nurse is educating a patient who is starting a new antidepressant medication. Which statement by the nurse is most accurate regarding the risk of suicidal thoughts and behaviors associated with antidepressant use?

A. "The risk of suicidal thoughts is highest during the first few weeks of treatment.": This is the most accurate statement. During the initial weeks of antidepressant therapy, especially in adolescents and young adults, the risk of suicidal ideation may increase as energy levels improve before mood stabilizes. Close monitoring during this period is critical. B. "Antidepressants eliminate the risk of suicidal thoughts in all patients.": While antidepressants help many patients, they do not eliminate the risk of suicidal thoughts. Some individuals may continue to experience or even develop new suicidal ideation, particularly early in treatment. C. "Suicidal thoughts are a common side effect experienced by most patients.": Suicidal ideation is a serious but not common side effect. It occurs in a subset of patients, particularly younger individuals, and must be monitored closely, but it is not experienced by the majority. D. "Suicidal thoughts only occur in patients with a history of suicide attempts.": Suicidal ideation can develop in individuals without a previous history. Risk factors include age, underlying psychiatric conditions, and individual response to medication—not just past behavior.