A nurse is monitoring an elderly client in a geriatric care unit. Exhibits Which 2 anti-glycemic agents are most appropriate for managing glycemic levels in this client?

Rationale: A. Inhaled anticholinergics are used for chronic obstructive pulmonary disease (COPD) and asthma, not for glycemic control. B. Sulfonylureas (e.g., glipizide, glyburide) stimulate insulin secretion from the pancreas and are appropriate for lowering blood glucose in type 2 diabetes. C. Metformin is a biguanide that decreases hepatic glucose production and improves insulin sensitivity, making it a first-line oral agent for type 2 diabetes. D. Beta 2-adrenergic agonists (e.g., albuterol) are bronchodilators used in asthma and COPD; they may actually raise blood glucose, so they are not appropriate. E. Mast cell stabilizers (e.g., cromolyn) are used in allergy and asthma management, not for diabetes.