A nurse is planning care for a client who is to receive a prescription for IV vancomycin. Which of the following interventions should the nurse include in the plan?

A. Examine the client's upper body for flushing of the skin during the infusion: Red man syndrome is a common adverse effect of rapid IV vancomycin administration. It presents as flushing or rash on the upper body, and monitoring for this reaction is essential to ensure client safety. B. Monitor for hypertension while the medication infuses: Vancomycin is more commonly associated with hypotension rather than hypertension during infusion, so monitoring for high blood pressure is not a primary concern. C. Check for a penicillin cross-sensitivity before infusing the medication: Vancomycin is not a beta-lactam antibiotic, so penicillin allergy does not predict vancomycin reactions. Screening for cross-sensitivity is not required. D. Infuse the medication over 30 min: Rapid infusion increases the risk of adverse effects such as red man syndrome. Vancomycin should typically be infused over at least 60 minutes or longer, depending on the dose, to reduce this risk.