A nurse is planning to administer medications to a client who weighs 198 lb. The prescription reads, "filgrastim 5 mcg/kg, subcutaneous, daily." Available is filgrastim 300 mcg/mL. How many mL should the nurse plan to give with each dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Convert the client's weight from pounds to kilograms, knowing that 1 kilogram equals 2.2 pounds. The client weighs 198 pounds, which is approximately 90 kilograms (198 lb / 2.2). The prescription specifies a dosage of 5 micrograms per kilogram, so the client requires 450 micrograms of filgrastim (90 kg * 5 mcg/kg). Since the available filgrastim concentration is 300 micrograms per milliliter, divide the required dose by the concentration to find the volume in milliliters: 450 mcg / 300 mcg/mL equals 1.5 mL. Therefore, the nurse should plan to administer 1.5 mL of filgrastim for each dose.