A nurse is planning to teach a client about taking prednisone. Which of the following instructions should the nurse include?

A. Prednisone should be taken with food to prevent gastrointestinal irritation. B. Weight gain, not weight loss, is a common side effect due to fluid retention and increased appetite. C. Prednisone should be taken in the morning, as it can cause insomnia if taken at bedtime. D. Prednisone is a corticosteroid that increases the risk of osteoporosis by reducing calcium absorption, so clients should increase dietary calcium and vitamin D intake.