A nurse is preparing an in-service presentation on medication classifications. Which of the following medications are considered opioid antagonists? (Select All That Apply.)

A. Oxycodone is an opioid agonist, not an antagonist. It is used for pain management. B. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID), not an opioid antagonist. It is used to reduce inflammation and pain. C. Naltrexone is an opioid antagonist that blocks the effects of opioids and is used for treating opioid addiction and alcohol use disorder. D. Naloxone (Narcan) is an opioid antagonist used to reverse opioid overdose by blocking the effects of opioids on the brain.