A nurse is preparing to administer acyclovir 5 mg/kg via intermittent IV bolus to a client who weighs 138 lb. Available is acyclovir 7 mg/mL of 0.9% sodium chloride solution. How many mL should the nurse administer? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Calculation: Convert the client's weight from pounds (lbs) to kilograms (kg): Formula: Weight in kg = Weight in lbs / 2.2 lbs/kg = 138 lbs / 2.2 lbs/kg ≈ 62.73 kg Calculate the total dose of acyclovir needed in milligrams: Ordered dose: 5 mg/kg Client's weight in kg: ≈ 62.73 kg Formula: Total dose (mg) = Ordered dose (mg/kg) × Client's weight (kg) = 5 mg/kg × 62.73 kg ≈ 313.65 mg Determine the concentration of the available acyclovir solution: Available concentration: 7 mg/mL Calculate the volume of acyclovir to administer: Formula: Volume to administer (mL) = Desired dose (mg) / Concentration (mg/mL) = 313.65 mg / 7 mg/mL ≈ 44.81 mL Round the answer to the nearest whole number: 44.81 Ml rounded to the nearest whole number is 45 mL.