A nurse is preparing to administer amoxicillin and clavulanate 30 mg/kg/day PO divided in equal doses every 12 hr to an infant who weighs 16 lb. Available is amoxicillin and clavulanate suspension 125 mg/5 mL suspension. How many mL should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

To calculate the dosage of amoxicillin and clavulanate for the infant, we first convert the weight from pounds to kilograms, knowing that 1 pound is approximately 0.453592 kilograms. The infant weighs 16 pounds, which is roughly 7.25748 kilograms. The prescribed dose is 30 mg/kg/day, so for the infant, it would be 30 mg/kg/day * 7.25748 kg = 217.7244 mg/day. Since the medication is to be administered every 12 hours, the daily dose should be divided into two, resulting in 217.7244 mg/day / 2 = 108.8622 mg per dose. With the medication available in a concentration of 125 mg/5 mL, we calculate the volume per dose as (108.8622 mg * 5 mL) / 125 mg = 4.354488 mL per dose. Rounding to the nearest tenth, the nurse should administer 4.4 mL per dose.