A nurse is preparing to administer amoxicillin and clavulanate 30 mg/kg/day PO divided in equal doses every 12 hr to an infant who weighs 16 lb. Available is amoxicillin and clavulanate suspension 125 mg/5 mL suspension. How many mL should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Calculation: Convert the infant's weight from pounds (lb) to kilograms (kg) using the conversion factor of 2.2 lb/kg. Patient's weight in kg = 16 lb / 2.2 lb/kg = 7.2727 kg. Calculate the total daily dose in milligrams (mg) for the child. Total daily dose = Ordered dose (mg/kg/day) × Patient's weight (kg) = 30 mg/kg/day × 7.2727 kg = 218.181 mg/day. Calculate the dose per administration (every 12 hr, which is 2 doses per day). Dose per administration = Total daily dose (mg/day) / 2 doses/day = 218.181 mg / 2 = 109.09 mg/dose. Determine the concentration of the available medication. The available concentration is 125 mg in 5 mL. Concentration = 125 mg / 5 mL = 25 mg/mL. Calculate the volume in milliliters (mL) to administer per dose. Volume (mL) = Dose per administration (mg) / Concentration (mg/mL) = 109.09 mg / 25 mg/mL = 4.3636 mL. Round the answer to the nearest tenth. = 4.4 mL.