A nurse is preparing to administer clindamycin 10 mg/kg/day PO in three divided doses to a child who weighs 53 lb. Available is clindamycin oral solution 75 mg/S mL. How many mL should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)
Explanation & Rationale
Convert the child's weight from pounds to kilograms: There are 2.205 pounds in 1 kilogram. 53 lb = 53 lb / 2.205 lb/kg = 24.04 kg (rounded to two decimal places). Determine the total daily dosage: The child is prescribed 10 mg/kg/day of clindamycin. The child weighs 24.04 kg. The total daily dosage is 10 mg/kg/day x 24.04 kg = 240.4 mg/day. Calculate the dosage per dose: The medication is to be administered in three divided doses. The dosage per dose is 240.4 mg/day / 3 doses = 80.133 mg/dose. Determine the volume per dose: The clindamycin oral solution contains 75 mg per 5 mL. The nurse needs to administer 80.133 mg per dose. To find the volume per dose: 75 mg / 5 mL = 80.133 mg / x mL Cross-multiplying gives us: 75x = 400.665 Dividing both sides by 75, we get: x = 5.3422 mL Round the answer to the nearest tenth: Rounding 5.3422 to the nearest tenth gives us 5.3 mL.