A nurse is preparing to administer cyclosporine 5 mg/kg IV bolus to a client who weighs 143 lb. Available is cyclosporine injection 50 mg/mL. How many mL should the nurse administer? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Calculation: Convert the client's weight from pounds (lbs) to kilograms (kg): Formula: Weight in kg = Weight in lbs / 2.2 lbs/kg = 143 lbs / 2.2 lbs/kg ≈ 65 kg Calculate the total dose of cyclosporine needed: Ordered dose: 5 mg/kg Client's weight in kg: 65 kg Formula: Total dose (mg) = Ordered dose (mg/kg) × Client's weight (kg) = 5 mg/kg × 65 kg = 325 mg Determine the concentration of the available cyclosporine injection: Available concentration: 50 mg/mL Calculate the volume of cyclosporine to administer: Formula: Volume to administer (mL) = Desired dose (mg) / Concentration (mg/mL) = 325 mg / 50 mg/mL = 6.5 mL