A nurse is preparing to administer dexamethasone 0.5 mg/kg/day IM to divide equally every 6 hr to a client who weighs 132 lb. Available is dexamethasone 4 mg/mL. How many ml should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)
Explanation & Rationale
Convert the client's weight from pounds (lb) to kilograms (kg). Weight in kg = 132 lb / 2.2 lb/kg = 60 kg Calculate the total daily desired dose in milligrams (mg). Total daily desired dose (mg) = Desired dose (mg/kg/day) × Weight (kg) = 0.5 mg/kg/day × 60 kg = 30 mg/day. Calculate the number of doses per day. Doses are administered every 6 hr, so Number of doses per day = 24 hr / 6 hr = 4 doses/day. Calculate the dose per administration in milligrams (mg). Dose per administration (mg) = Total daily desired dose (mg) / Number of doses per day = 30 mg / 4 doses = 7.5 mg. Available concentration of the dexamethasone injection = 4 mg/mL. Calculate the volume in milliliters (mL) to administer per dose. Volume per dose (mL) = Desired dose per administration (mg) / Available concentration (mg/mL) = 7.5 mg / 4 mg/mL = 1.875 mL. Round the answer to the nearest tenth. = 1.9 mL.