A nurse is preparing to administer esomeprazole 20 mg IV bolus in 100 mL 5% dextrose in water for a client who has peptic ulcer disease. Available is esomeprazole 40 mg/5 mL. How many milliliters should the nurse add to the 5% dextrose in water? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Calculation: Identify the ordered dose and available concentration Ordered Dose: 20 mg Available Concentration: 40 mg/5 mL Calculate the volume to administer Volume to administer = (Ordered Dose ÷ Concentration) × Volume of Concentration Volume to administer = (20 ÷ 40) × 5 Volume to administer = 0.5 × 5 Volume to administer = 2.5 mL