A nurse is preparing to administer fligrastin 5 mcg/kg subcutaneous to a client who weighs 143 lb. Available is fligrastin 300 mcg/mL. How many mL should the nurse administer? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Calculation: Convert the client's weight from pounds (lbs) to kilograms (kg): Formula: Weight in kg = Weight in lbs / 2.2 lbs/kg = 143 lbs / 2.2 lbs/kg ≈ 65 kg Calculate the total dose of filgrastim needed in micrograms: Ordered dose: 5 mcg/kg Client's weight in kg: 65 kg Formula: Total dose (mcg) = Ordered dose (mcg/kg) × Client's weight (kg) = 5 mcg/kg × 65 kg = 325 mcg Determine the concentration of the available filgrastim solution: Available concentration: 300 mcg/mL Calculate the volume of filgrastim to administer: Formula: Volume to administer (mL) = Desired dose (mcg) / Concentration (mcg/mL) = 325 mcg / 300 mcg/mL ≈ 1.0833 mL Round the answer to the nearest tenth: 1.0833 mL rounding to the nearest tenth gives us 1.1 mL.