A nurse is preparing to administer mannitol via continuous IV infusion to a client. Which of the following findings should the nurse identify as an expected outcome of this medication therapy?

Choice A rationale Mannitol is an osmotic diuretic that increases the osmolality of the glomerular filtrate, thereby inhibiting water reabsorption in the renal tubules. This osmotic effect leads to increased water excretion and subsequently an improved urinary output. This enhanced diuresis is a primary therapeutic goal, particularly in conditions like cerebral edema or acute renal failure. Choice B rationale Mannitol is not indicated for the resolution of diabetic ketoacidosis. Diabetic ketoacidosis is a metabolic emergency characterized by hyperglycemia, ketonemia, and acidosis, requiring insulin therapy, fluid resuscitation, and electrolyte management. Mannitol does not address the underlying pathophysiology of insulin deficiency. Choice C rationale Mannitol's mechanism of action does not directly decrease brain natriuretic peptide (BNP) levels. BNP is a hormone released by cardiomyocytes in response to ventricular stretch and is a marker of heart failure. While mannitol can reduce fluid overload, which might indirectly impact cardiac preload, its direct effect is not on BNP secretion. Choice D rationale Mannitol is used to decrease, not increase, intraocular pressure. Its osmotic properties draw fluid from the extravascular space, including the vitreous humor of the eye, into the vascular compartment. This reduction in fluid volume within the eye lowers intraocular pressure, making it useful in treating acute angle-closure glaucoma.