A nurse is preparing to administer methimazole 0.3 mg/kg/day PO divided in equal doses every 8 hr to a school-age child who weighs 55 lb. Available is methimazole 5 mg tablets. How many tablets should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)
Explanation & Rationale
Identify the given information: Dose of methimazole: 0.3 mg/kg/day Weight of the child: 55 lb Concentration of methimazole tablets: 5 mg/tablet Convert the child's weight from pounds to kilograms: 1 lb ≈ 0.453592 kg Calculate the total daily dose of methimazole in mg: Total daily dose = Dose/kg/day x Weight (kg) Substitute the values: Total daily dose = 0.3 mg/kg/day x 55 lb x (0.453592 kg/1 lb) Total daily dose ≈ 7.48 mg Calculate the dose per dose (every 8 hours): Dose per dose = Total daily dose / 3 Substitute the values: Dose per dose = 7.48 mg / 3 Dose per dose ≈ 2.49 mg Calculate the number of tablets to be administered: Number of tablets = Dose per dose (mg) / Concentration (mg/tablet) Substitute the values: Number of tablets = 2.49 mg / 5 mg/tablet Number of tablets ≈ 0.498 Round the answer to the nearest tenth: Number of tablets ≈ 0.5 tablets