A nurse is preparing to administer milrinone 50 mcg/kg IV loading dose to a client who weighs 154 lb. Available is milrinone 1 mg/mL. How many mL should the nurse administer? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Convert the client's weight from pounds (lb) to kilograms (kg). Weight in kg = 154 lb / 2.2 lb/kg = 70 kg. Calculate the total desired dose in micrograms (mcg). Desired dose (mcg) = Desired dose (mcg/kg) × Weight (kg) = 50 mcg/kg × 70 kg = 3500 mcg. Convert the available concentration from milligrams per milliliter (mg/mL) to micrograms per milliliter (mcg/mL). 1 mg = 1000 mcg Available concentration in mcg/mL = 1 mg/mL × 1000 mcg/mg = 1000 mcg/mL. Calculate the volume in milliliters (mL) to administer. Volume (mL) = Desired dose (mcg) / Available concentration (mcg/mL) = 3500 mcg / 1000 mcg/mL = 3.5 mL.