A nurse is preparing to administer nitroprusside 1 mcg/kg/min to a newborn who weighs 8 lb 4 oz. Available is nitroprusside 50 mg in 0.9% sodium chloride. How many mL/hr? (Round the answer to the nearest tenth. Use a leading zero if it applies.)

Step 1: Convert the weight from pounds and ounces to kilograms. 8 lb 4 oz = 8.25 lb 8.25 lb ÷ 2.2 = 3.75 kg Step 2: Calculate the dose per minute. 1 mcg/kg/min × 3.75 kg = 3.75 mcg/min Step 3: Calculate the total dose per hour. 3.75 mcg/min × 60 min/hr = 225 mcg/hr Step 4: Determine the concentration of the solution. 50 mg = 50,000 mcg 50,000 mcg = 250 mL 225 mcg = (225 mcg × 250 mL) ÷ 50,000 mcg = 1.125 mL/hr Step 5: Round to the nearest tenth. 1.125 mL/hr ≈ 1.1 mL/hr The IV pump should be set to deliver 1.1 mL/hr.