A nurse is preparing to administer rifampin 20 mg/kg/day PO in two divided doses to a client who weighs 132 lb and has tuberculosis. The amount available is rifampin 150 mg capsules. How many capsules should the nurse administer per dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.) ________ capsule(s)

Step 1 is to convert the client's weight from pounds (lb) to kilograms (kg) Conversion factor: 1 kg = 2.2 lbs Weight in kg = 132 ÷ 2.2 132 ÷ 2.2 = 60 kg Step 2 is to calculate the total daily dose in milligrams (mg) Total Daily mg = Weight in kg × Dosage (mg/kg/day) Total Daily mg = 60 × 20 60 × 20 = 1200 mg/day Step 3 is to calculate the dose per administration (two divided doses) mg per dose = Total Daily mg ÷ 2 1200 ÷ 2 = 600 mg Step 4 is to calculate the number of capsules per dose Number of capsules = Ordered Dose ÷ Available Strength Number of capsules = 600 ÷ 150 600 ÷ 150 = 4 Step 5 is to round to the nearest whole number 4 = 4 Answer: 4 capsule(s)