A nurse is preparing to administer topotecan IV to a client. Which of the following medications should the nurse expect to administer to treat the adverse effects of topotecan?

A. "Cloudy" is not a medication and does not address any adverse effects related to topotecan. B. Granisetron is an antiemetic medication used to prevent nausea and vomiting, which are common adverse effects of topotecan. C. Insulin lispro is a rapid-acting insulin used to control blood sugar levels and does not relate to the adverse effects of topotecan. D. Docusate sodium is a stool softener used to prevent constipation, but it does not specifically address the nausea and vomiting associated with chemotherapy. E. Prednisone is a corticosteroid that may be used for other indications but is not primarily indicated for treating the nausea and vomiting caused by topotecan.