A nurse is preparing to administer topotecan IV to a client.Which of the following medications should the nurse expect to administer to treat the adverse effects of topotecan?

Choice A rationaleGranisetron is a serotonin antagonist used to prevent nausea and vomiting, common adverse effects of topotecan, an anticancer drug that targets DNA synthesis.Choice B rationaleInsulin lispro is a rapid-acting insulin used to manage blood glucose levels in diabetic patients, not to treat the adverse effects of topotecan.Choice C rationaleDocusate sodium is a stool softener used to treat constipation, which is not typically an adverse effect of topotecan. Nausea and vomiting are more common.Choice D rationalePrednisone is a corticosteroid used to reduce inflammation and suppress the immune system, but it is not typically used to treat nausea or vomiting caused by topotecan.