A nurse is preparing to administer topotecan IV to a client.Which of the following medications should the nurse expect to administer to treat the adverse effects of topotecan?

Choice A rationaleGranisetron is a 5-HT3 receptor antagonist used to treat chemotherapy-induced nausea and vomiting, a common adverse effect of topotecan.Choice B rationaleInsulin lispro is a rapid-acting insulin used to manage blood glucose levels in diabetic patients, not to treat adverse effects of topotecan.Choice C rationaleDocusate sodium is a stool softener used to prevent constipation by increasing the water content of stool, unrelated to topotecan's adverse effects.Choice D rationalePrednisone is a corticosteroid used to treat inflammation and immune responses, but it is not specifically indicated for the adverse effects of topotecan.