A nurse is preparing to administer vancomycin 15 mg/kg/day divided equally every 12 hr. The client weighs 198 lb. How many mg should the nurse administer with each dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Convert the client's weight from pounds (lb) to kilograms (kg) Given weight = 198 lb Conversion factor: 1 kg = 2.2 lb Weight (kg) = 198 lb / 2.2 lb/kg = 90 kg Calculate the Total Daily Dose (mg/day) Prescribed dose = 15 mg/kg/day Total Daily Dose (mg/day) = Weight (kg) x Dose (mg/kg/day) = 90 kg x 15 mg/kg/day = 1,350 mg/day Calculate the Single Dose (mg/dose) The total daily dose is divided equally every 12 hours (2 doses per day). Single Dose (mg) = Total Daily Dose / Number of doses per day = 1,350 mg / 2 = 675 mg