A nurse is preparing to administer vancomycin 15 mg/kg/day divided equally every 12 hr. The client weighs 198 lb. How many mg should the nurse administer with each dose?

43 Step 1 is: Convert the client's weight from pounds (lb) to kilograms (kg):. 198 lb ÷ (2.2 lb/kg) = 90 kg. Step 2 is: Calculate the total daily dosage of vancomycin in mg:. 90 kg × 15 mg/kg/day = 1350 mg/day. Step 3 is: Determine the dosage for each administration, as the total daily dose is divided equally every 12 hr (2 doses per day):. 1350 mg/day ÷ 2 doses/day = 675 mg/dose. The nurse should administer 675 mg with each dose.