A nurse is preparing to administer vancomycin 15 mg/kg/day divided equally every 12 hr. The client weighs 198 lb. How many mg should the nurse administer with each dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

To calculate the dosage of vancomycin, first convert the client's weight from pounds to kilograms, knowing that 1 kilogram equals 2.2 pounds. The client weighs 198 pounds, which is approximately 90 kilograms (198 ÷ 2.2). The prescribed dose is 15 mg/kg/day, so for a 90 kg individual, this would be 1350 mg/day (90 kg × 15 mg/kg). Since the dosage is divided equally every 12 hours, the nurse would administer half of the daily dosage per dose, resulting in 675 mg every 12 hours (1350 mg/day ÷ 2). Therefore, the nurse should administer 675 mg with each dose.