A nurse is preparing to administer vancomycin IV to a client. Which of the following medications may interact with vancomycin?

A. Nitroglycerin: Nitroglycerin is a vasodilator used to treat angina and does not have known interactions with vancomycin. Concurrent use does not increase the risk of vancomycin toxicity or adverse effects. B. Furosemide: Furosemide is a loop diuretic that can be nephrotoxic and ototoxic, similar to vancomycin. Using both medications concurrently increases the risk of kidney damage and hearing loss, requiring careful monitoring of renal function and auditory status. C. Calcium chloride: Calcium chloride is used for hypocalcemia and cardiac stabilization but does not interact directly with vancomycin. No enhanced toxicity or adverse reaction is expected when these drugs are administered together. D. Morphine: Morphine is an opioid analgesic with no direct interaction with vancomycin. While both drugs may depress the central nervous system in different ways, morphine does not increase the risk of vancomycin-related nephrotoxicity or ototoxicity.