A nurse is preparing to discharge a client newly diagnosed with peptic ulcer disease. The client's diagnostic test results were positive for H pylori bacteria. The health care provider has ordered the "triple therapy" regimen. Which medications will the nurse educate the client on?

A. Proton-pump inhibitor, an antibiotic, and bismuth salts: This combination is used in quadruple therapy, not triple therapy. Bismuth is typically included when patients fail first-line treatment or have contraindications to standard regimens. B. Proton-pump inhibitor and two antibiotics: Triple therapy involves a proton-pump inhibitor (like omeprazole or lansoprazole) and two antibiotics, commonly clarithromycin and either amoxicillin or metronidazole. This regimen is designed to eradicate H. pylori and promote ulcer healing. C. H2-receptor antagonist and two antibiotics: H2-receptor antagonists like ranitidine are not part of the standard triple therapy. They are less effective than PPIs in suppressing gastric acid and are not the preferred first-line treatment with antibiotics. D. H2-receptor antagonist, proton-pump inhibitor, and an antibiotic: This combination is incorrect for triple therapy. Using both an H2-receptor antagonist and a PPI is redundant and not evidence-based. Triple therapy requires a PPI and two antibiotics, not one.