ATI NUR 180 Pharmacology Proctored Exam
A nurse is preparing to educate a patient who has newly been prescribed sucralfate (Carafate) for the management of peptic ulcer disease (PUD). What is the mechanism of action for this medication?
Explanation & Rationale
Choice B rationaleSucralfate (Carafate) acts by forming a viscous, adhesive substance that binds to the ulcer site, creating a physical barrier protecting it from stomach acid and allowing healing.Choice A rationaleSucralfate does not function as an endogenous prostaglandin; it does not mimic or enhance prostaglandin activity in the GI tract.Choice C rationaleSucralfate does not neutralize gastric acid; that is the function of antacids.Choice D rationaleSucralfate does not antagonize H2 receptors on parietal cells; H2 receptor antagonists are a different class of medication.
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