A nurse is providing an in-service on the complications of naloxone (Narcan), such as abstinence syndrome. Which of the following signs and symptoms should the nurse include in her in-service about abstinence syndrome?

A. Pinpoint pupils, coma, and respiratory depression: These are signs of opioid overdose, not abstinence syndrome. B. Sedation, fixed pupils, and nausea: This may be associated with opioid overdose, not withdrawal. C. Fever, hypertension, vomiting, anxiety, and abdominal cramping: These are classic symptoms of abstinence syndrome (withdrawal symptoms) after naloxone administration. D. Hyperventilation, depression, and constipation: These are not typical signs of abstinence syndrome.