A nurse is providing care to a client with arthritis in several large weight-bearing joints who is receiving NSAID therapy. Which nursing diagnosis would be most appropriate?

A. Risk for Unstable Blood Glucose Levels: NSAIDs are not associated with blood glucose fluctuations. This diagnosis would be more appropriate for clients with diabetes or those on medications like corticosteroids that affect glucose metabolism. B. Impaired Gas Exchange: This diagnosis is unrelated to arthritis or NSAID use unless there is a separate respiratory condition. Neither the disease nor its treatment directly compromises oxygen-carbon dioxide exchange in the lungs. C. Risk for Imbalanced Body Temperature: NSAIDs may reduce fever, but clients with arthritis are not usually at risk for temperature imbalance. This diagnosis would not reflect the primary concern related to joint inflammation and pain. D. Impaired Physical Mobility: Arthritis in large weight-bearing joints often results in pain, stiffness, and reduced range of motion. NSAID therapy is aimed at improving mobility, making this the most relevant nursing diagnosis for this client.