A nurse is providing discharge instructions to a patient who has been prescribed Acetaminophen for pain management. Which of the following statements by the patient indicates the need for further teaching?

A. "If my pain persists, I can safely increase the dose to 1500 mg every 4–6 hours.": This dose exceeds the maximum safe limit for acetaminophen. The recommended adult dose is no more than 1000 mg per dose and 4000 mg per day. Exceeding this can lead to serious hepatotoxicity, especially with prolonged use or preexisting liver conditions. B. "I should use caution when taking acetaminophen with warfarin as it may affect my INR levels.": Acetaminophen can increase the anticoagulant effect of warfarin, possibly elevating INR and increasing the risk of bleeding. Regular monitoring is recommended when both drugs are used concurrently. C. "I need to be cautious when taking other medications that may contain acetaminophen.": Many over-the-counter medications, such as cold and flu remedies, also contain acetaminophen. Accidental overdose can occur if this is not considered when calculating total daily intake. D. "I should contact my healthcare provider if I experience yellowing of the skin or eyes.": Jaundice may be a sign of liver damage or failure due to acetaminophen toxicity. Early recognition of this symptom is critical for preventing serious complications.