A nurse is providing discharge teaching for a patient with insulin glargine (Lantus). Which instructions are correct? SELECT ALL THAT APPLY

Rationale: A. Insulin glargine is a long-acting basal insulin that is not compatible with other insulins in the same syringe due to its pH and formulation. Mixing it can alter its action, making blood glucose control unpredictable and unsafe. B. Glargine provides a steady, peakless insulin level, which mimics basal insulin secretion and reduces the risk of hypoglycemia that can occur with peak insulin activity. This characteristic distinguishes it from short- or intermediate-acting insulins. C. Glargine is long-acting and not meal-dependent, unlike rapid- or short-acting insulin. Timing it with meals is unnecessary and may lead to inadequate coverage or hypoglycemia if meals are delayed. D. Consistent timing maintains stable basal insulin levels and helps achieve predictable 24-hour glycemic control. Deviating from the schedule may result in hyperglycemia or hypoglycemia. E. Glargine is designed to provide a continuous, long-acting basal insulin effect for up to 24 hours, supporting overall glycemic stability and reducing the need for multiple daily injections for basal coverage.