A nurse is providing discharge teaching to a client who has asthma and a new prescription for fluticasone/salmeterol. For which of the following adverse effects should the nurse instruct the client to report to the provider?

A. Dry oral mucous membranes – While mild dryness may occur, it is not a serious adverse effect that typically requires provider notification. B. Increased appetite – This is not a common or expected adverse effect of fluticasone/salmeterol. C. Sedation – Fluticasone/salmeterol is not known to cause sedation; it contains a corticosteroid and a long-acting beta-agonist (LABA). D. White coating in the mouth – This may indicate oral candidiasis (thrush), a fungal infection that can result from inhaled corticosteroid use like fluticasone. Clients should be taught to rinse their mouth after each use and report any signs of infection to the provider.