A nurse is providing discharge teaching to a client who has schizophrenia and is starting therapy with clozapine. Which of the following is the highest priority for the client to report to the provider?

A. Blurred vision: Blurred vision can occur as a side effect of clozapine due to anticholinergic properties. While it may cause discomfort or temporary visual disturbances, it is not immediately life-threatening and does not require urgent reporting to the provider. B. Dry mouth: Dry mouth is a common and expected anticholinergic side effect of clozapine. Although it can contribute to dental issues if persistent, it does not indicate a serious or emergent complication and can often be managed with hydration or saliva substitutes. C. Fever: Fever is the highest priority symptom to report because it can indicate agranulocytosis, a rare but potentially life-threatening side effect of clozapine. Agranulocytosis compromises the immune system, increasing the risk of severe infections, making early detection and intervention critical. D. Constipation: Constipation is a common side effect due to clozapine’s anticholinergic effects. While it should be monitored and managed to prevent complications such as bowel obstruction, it is not immediately life-threatening compared to signs of infection like fever.