A nurse is providing patient education to a 55-year-old man who has been prescribed opioids for chronic back pain. Which of the following statements by the nurse is most appropriate when educating the patient about opioid-induced constipation?

A. "Opioid-induced constipation typically resolves on its own after a few weeks of treatment.": This is incorrect. Unlike other opioid side effects such as nausea or sedation, constipation does not typically resolve over time. It often persists and requires proactive management throughout opioid therapy. B. "Avoid physical activity to prevent exacerbating your back pain.": While activity should be adjusted to the patient’s condition, light physical activity like walking actually helps stimulate bowel function. Complete avoidance of movement can worsen constipation. C. "Start taking stool softeners along with your opioid medication.": This is the most appropriate advice. Prophylactic use of stool softeners or stimulant laxatives is recommended when initiating opioid therapy, as constipation is a nearly universal side effect due to slowed gastrointestinal motility. D. "You should wait to see if constipation develops before taking any specific measures.": Waiting for constipation to develop can lead to discomfort and complications like fecal impaction. Preventive strategies should be started as soon as opioid treatment begins.