A nurse is providing teaching to a client newly diagnosed with systemic lupus erythematosus (SLE). Which statement should the nurse include in the teaching?

A. While SLE and its treatments (such as corticosteroids and immunosuppressants) increase the risk of infection, advising a client to avoid all contact with loved ones until remission is socially isolating and clinically unnecessary. Instead, the nurse should teach standard infection prevention measures like frequent handwashing and avoiding individuals with known illnesses. Psychosocial support is vital for patients with chronic autoimmune diseases. B. SLE primarily targets the skin, joints, kidneys, and serous membranes rather than being a primary driver of chronic liver disease. While some medications used for SLE can be hepatotoxic, liver failure is not the hallmark complication of the disease itself. The nursing education should focus on the organs most frequently damaged by the autoimmune process, such as the kidneys and the cardiovascular system. C. Lupus nephritis is a severe and common complication of SLE, occurring when immune complexes deposit in the glomeruli and trigger inflammation. Significant weight gain and peripheral edema are early clinical indicators of renal impairment and protein loss in the urine. Teaching the client to monitor for these symptoms ensures early detection and intervention, which is critical for preserving long-term renal function. D. SLE is not a primary risk factor for the development of diabetes mellitus, although long-term use of corticosteroids for SLE management can lead to secondary hyperglycemia. However, the disease process of lupus itself focuses on systemic inflammation and tissue damage rather than insulin resistance. Focusing teaching on diabetes distracts from the more prevalent and immediate risks of vasculitis and organ-specific lupus flares.