A nurse is providing teaching to a client who has a depressive disorder and a new prescription for amitriptyline. Which of the following statements by the client indicates an understanding of the teaching?

A. Incorrect – Amitriptyline can cause orthostatic hypotension, not increased blood pressure. B. Correct – Tricyclic antidepressants like amitriptyline take 2–4 weeks to show therapeutic effects. C. Incorrect – St. John's wort can increase the risk of serotonin syndrome and should not be taken with antidepressants. D. Incorrect – Amitriptyline should be taken with food to minimize gastrointestinal upset.