A nurse is providing teaching to a client who has a depressive disorder and a new prescription for amitriptyline. Which of the following statements by the client indicates an understanding of the teaching?

Rationale: A. Amitriptyline, a tricyclic antidepressant (TCA), commonly causes orthostatic hypotension, not hypertension. B. TCAs require 2 to 4 weeks to achieve therapeutic effect. Informing clients of this delay encourages adherence and sets realistic expectations. C. Amitriptyline should be taken with or after meals to reduce gastric irritation. D. St. John’s wort should not be used with TCAs due to risk of serotonin syndrome and potential drug interactions.