A nurse is providing teaching to a client who has a depressive disorder and a new prescription for amitriptyline. Which of the following statements by the client indicates an understanding of the teaching?

A. Amitriptyline is more likely to cause a decrease in blood pressure, especially when standing (orthostatic hypotension), rather than an increase. B. St. John’s wort should not be taken with amitriptyline as it can interact and increase the risk of serotonin syndrome. C. It typically takes 2-4 weeks for amitriptyline to show therapeutic effects. D. Amitriptyline is usually taken with food to minimize gastrointestinal discomfort.