A nurse is providing teaching to a client who has a duodenal ulcer and is starting to take sucralfate. Which of the following instructions should the nurse include in the teaching?

Choice A rationale Sucralfate should be taken on an empty stomach, not with meals, to ensure it coats the ulcer effectively. Choice B rationale There is no need to reduce dietary fiber while taking sucralfate. Fiber intake does not interfere with the medication’s effectiveness. Choice C rationale Antacids should not be taken within 30 minutes before or after taking sucralfate, as they can interfere with its action. Choice D rationale Increasing fluid intake is recommended while taking sucralfate to help prevent constipation, a common side effect of the medication.