A nurse is providing teaching to a client who has a new prescription for rifampin. Which of the following statements should the nurse include in the teaching?

A. "Your urine will turn orange while you are taking this medication.": Rifampin commonly causes a harmless orange discoloration of body fluids such as urine, sweat, tears, and saliva. Clients should be informed beforehand to prevent alarm and to avoid staining of clothing or contact lenses. B. "This medication will not interfere with the effectiveness of oral contraceptives.": Rifampin induces hepatic enzymes that increase the metabolism of oral contraceptives, reducing their effectiveness. Clients should use alternative or additional non-hormonal birth control methods. C. "You can continue to wear soft contact lenses while taking this medication.": Rifampin can permanently discolor soft contact lenses due to its orange pigment. Clients should be advised to wear glasses during therapy to avoid staining. D. "You should take this medication once each day at bedtime.": Rifampin is usually taken on an empty stomach either 1 hour before or 2 hours after meals to enhance absorption, not specifically at bedtime unless directed by the provider.